A recent study has found that coffee could be effective against fighting Parkinson’s disease in the brain. Scientists have found that there are certain components present in coffee which works for preventing this disease. Parkison’s disease has been spreading on a large scale and researchers have not been able to find any cure for it. However, there are medicines available to help to deal with the symptoms of Parkinson’s disease. It is caused due to the build-up of a specific type of misfolded protein in the brain. The protein, alpha-synuclein is responsible for causing Parkinson’s disease by joining with other compounds in the brain. This protein transfers from one neuron to another and hence spreads across different regions of the brain.
There are many compounds present in coffee which help protect against Parkison’s disease. However, from various studies, researchers concluded that apart from caffeine, there is a compound called eicosanoyl-5-hydroxytryptamine (EHT) which helps to prevent Parkinson’s disease. EHT reduces the building up of alpha-synuclein in the brain. EHT is a fatty acid derivative of serotonin which is found in the waxy coating of coffee beans. This compound has neuroprotective and anti-inflammatory properties.
Researchers experimented with mice to find the effectiveness of coffee for fighting against Parkinson’s disease. They separately gave doses of caffeine and EHT to mice to know about the results of the experiments. However, they found that neither of the two compounds works to reduce the build-up of alpha-synuclein protein. When the two compounds were given collectively to mice then the production of protein alpha-synuclein reduces significantly. Also, an improvement in the behavioral activities was also noticed in the mice. Still, more research needs to be carried out related to this subject. But this research has opened new avenues for researchers to explore.
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